Dra. Gabrielle B. Britton

Líneas o especialidades de investigación:

Estudios básicos y clínicos en cognición, aprendizaje y memoria, enfermedades neurodegenerativas y trastornos de ánimo asociados a la edad.

Resumen de la hoja de vida:

Completó la Licenciatura en Psicología en Vanderbilt University (1991), una Maestría en Psicología del Comportamiento en Mount Holyoke College en Massachusetts (1994) y un Doctorado en Neurociencia y Psicología de Indiana University en Bloomington (2000). Fue profesora en la Facultad de Psicología y el Programa en Neurociencias de Lafayette College en Pennsylvania del 2001-2006, y regresó a Panamá en el 2006 por medio de un subsidio de repatriación de SENACYT. Su investigación actual consiste de estudios básicos y clínicos que examinan la interacción de los procesos cognitivos y fisiológicos en trastornos de la memoria, con el objetivo de identificar biomarcadores de envejecimiento exitoso y patológico que faciliten el diagnóstico precoz de la demencia. Su atención se centra en el deterioro cognitivo relacionado con la edad, incluyendo su progresión a la enfermedad de Alzheimer. Ha recibido subsidios de SENACYT, National Institutes of Health (NIH) de EE.UU., Lindback Foundation y el Arturo Melo Brain Research Project. En el 2012 fundó el Panama Aging Research Initiative (PARI; @memoriaysalud), una iniciativa de colaboración nacional para fomentar la investigación enfocada en la salud de adultos mayores en Panamá. La Dra. Britton es colaboradora del grupo de trabajo Global Burden of Disease study, Investigadora Asociada de la Universidad Santa María la Antigua (USMA) de Panamá y la Universidad del Sur de Florida (University of South Florida Health), es becaria de Fulbright (2005), miembro de la Junta de Síndicos de la Fundación Ciudad del Saber y miembro del movimiento Ciencia en Panamá.

Publicaciones seleccionadas:

Britton GB, O’Bryant SE, Johnson LA, Hall JR, Villarreal AE, Oviedo DC, Perez-Lao AR, Carreira MB, Panama Aging Research Initiative (2019). Inflammatory biomarkers, depressive symptoms and falls among elderly in Panama. Current Aging Science, doi: 2174/1874609812666190215125104. [Epub ahead of print].

Carreira MB, Cossio R, Britton GB (2017). Individual and sex differences in high and low responder phenotypes. Behavioural Processes, 136, 20-27. doi: 10.1016/j.beproc.2017.01.006. PMID: 28088551.

Cossio R, Carreira MB, Vásquez CE, Britton GB (2016). Sex differences and estrous cycle effects on foreground contextual fear conditioning. Physiology and Behavior, 163, 305-311. doi: 10.1016/j.physbeh.2016.05.026. PMID: 27195460.

Dicker D. et al. (2018) Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1684-1735. doi: 10.1016/S0140-6736(18)31891-9. PMID: 30496102.

Fullman N et al. (2018). Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016. The Lancet. doi: 10.1016/S0140-6736(18)30994-2.

Hay SI et al. (2017). Global, regional and national disability-adjusted life years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1260-1344. doi: 10.1016/S0140-6736(17)32130-X.

James SL et al. (2018). Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1789-1858. doi: 10.1016/S0140-6736(18)32279-7. PMID: 30496104.

Kyu HH et al. (2018). Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1859-1922. doi: 10.1016/S0140-6736(18)32335-3. PMID: 30415748.

Lozano R. et al. (2018). Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 2091-138. doi: 10.1016/S0140-6736(18)32281-32285. PMID: 30496107.

Murray CJL et al. (2018). Population and fertility by age and sex for 195 countries and territories, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1995-2051. doi: 10.1016/S0140-6736(18)32278-5. PMID: 30496106.

O’Bryant SE, Edwards M, Johnson L, Hall J, Villarreal AE, Britton GB, Quiceno M, Munro Cullum C, Graff-Radford NR (2016). A blood screening test for Alzheimer’s disease. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 3, 83-90. doi: 10.1016/j.dadm.2016.06.004. PMID: 27453929.

O’Bryant SE, Mielke M, Rissman R, Lista S, Vanderstichele H, Zetterberg H, Lewczuk P, Posner H, Hall J, Johnson L, Fong YL, Luthman J, Jeromin A, Batrla-Utermann R, Villarreal AE, Britton GB, Snyder PJ, Henriksen K, Grammas P, Gupta V, Martins R, Hampel H (2017). Blood Based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic. Alzheimer’s & Dementia, 13(1), 45-48. doi: 10.1016/j.jalz.2016.09.014. PMID: 27870940.

Oviedo D, Lezcano H, Perez AR, Villarreal AE, Carreira MB, Isaza B, Wesley L, Grajales SA, Fernandez S, Frank A, Britton GB (2018). Vascular biomarkers and ApoE4 expression in mild cognitive impairment and Alzheimer’s disease. AIMS Neuroscience,5(2), 148-161. doi: 10.3934/Neuroscience.2018.2.148.

Roth GA et al. (2018). Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1736-1788. doi: 10.1016/S0140-6736(18)32203-7. PMID: 30496103.

Stanaway JD et al. (2018). Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 392(10159), 1923-1994. doi: 10.1016/S0140-6736(18)32225-6. PMID: 30496105.

Villarreal AE, Grajales S, López L, Britton GB, Panama Aging Research Initiative (2015). Cognitive impairment, depression and co-occurrence of both among the elderly in Panama: differential associations with multimorbidity and functional limitations. BioMed Research International, Article ID 718701. doi: 10.1155/2015/718701. PMID: 26798641.

Villarreal AE, Grajales S, López L, Oviedo DC, Carreira MB, Gómez LA, Montalván A, Vásquez V, Britton GB, Panama Aging Research Initiative (2018). Limitations in activities of daily living among dementia-free older adults in Panama. Ageing International, 43(2), 237-253 doi: 10.1007/s12126-018-9321-2.

Villarreal AE, Grajales S, O’Bryant SE, Edwards M, López L, Montalván A, Britton GB, Panama Aging Research Initiative (2016). Characterization of Alzheimer’s disease and mild cognitive impairment in older adults in Panama. Journal of Alzheimer’s Disease, 54, 897-901. doi: 10.3233/JAD-160402. PMID: 27567849.

Villarreal AE, O’Bryant SE, Edwards M, Grajales S, Britton GB for the Panama Aging Research Initiative (2016). Serum-based protein profiles of Alzheimer’s disease and mild cognitive impairment in elderly Hispanics. Neurodegenerative Disease Management, 6(3), 203-13. doi: 10.2217/nmt-2015-0009. PMID: 27229914.

Villarreal AE, Pérez-Lao AR, Oviedo DC, Grajales S, Carreira MB, Britton GB for the Panama Aging Research Initiative (2019). The Panama Aging Research Initiative longitudinal study. MEDICC Review, 21(2-3), 54-58.

Dra. Gabrielle Britton

Dra. Gabrielle B. Britton

Máximo grado de estudios: Ph.D., Indiana University, EE.UU., 2000.

Categoría: Investigador, Centro de Neurociencias y Unidad de Investigación Clínica.

Nivel SNI: Investigador Distinguido.

Información de contacto:

Correo: gbritton@indicasat.org.pa
Teléfono:  +507 517 0735+507 517 0708