Research lines or specialties:
Pharmacology, natural products, marine fungi, plants, sponges, hypertension, new drug targets to treat cardiovascular diseases, G-protein coupled receptors, confocal microscopy, confocal fluorescence spectroscopy, cell bioassays, pharmaceutical analysis.
Summary of resume:
Graduated from the Faculty of Pharmacy of the University of Panama in 1996. In 1998 she joined the Pharmacognosy Laboratory of Professors Arnold Vlietinck and Luc Pieters at the University of Antwerp, Belgium, where she received the degree of Doctor of Pharmaceutical Sciences in 2002 and with whom it collaborates for the creation of the first laboratory for the quality control of herbal products in Panama. In 2011, he received the TWAS-APANAC Award for Young Researchers for his studies on the marine pharmacology of natural products. She is currently a scientific researcher at INDICASAT AIP in Panama. She has edited and contributed to the book on “Intellectual Property Rights in Developing Countries” and is the manager of the INDICASAT AIP Intellectual Property Office. His research interests include the search for novel and renewable sources of bioactive natural products, the application of new methods to define their pharmacology, and the development of quality control systems for herbal products.
Selected publications:
Catherina C. Caballero-George et al., Fluorescence Correlation Spectroscopy in Drug Discovery: Study of Alexa532-endothelin 1 binding to the endothelin ETA receptor to describe the pharmacological profile of natural products. TheScientificWorldJournal, doi:10.1100/2012/524169, 2012
Catherina Caballero-George and Leonardo Uribe. Intellectual Property System in Panama: Biodiversity and Traditional Knowledge. En: Intellectual Property Rights Management in Developing Countries. 2012. Editorial: DAYA Publishing House, New Delhi, India
Jessica Bolaños et al., Study of the phylogenetic diversity of sponge-associated fungi isolated from highly diverse areas in the Republic of Panama and their effect on angiotensin and endothelin receptors. Marine Biotechnology [Aceptado] Abril, 2015
Nadir Planes y Catherina Caballero-George. Marine and soil derived natural products: A new source of novel cardiovascular protective agents targeting the endothelin system. Planta Medica, En imprenta, Ene, 2015
Ruba Bahem et al., Modulation of calcium signaling of angiotensin AT1, endothelin ETA and ETB receptors by silibinin, quercetin, crocin, diallyl sulfides and ginsenoside Rb1. Planta Medica, En imprenta Ene, 2015
Edgar Marin et al., Critical Evaluation of Biodegradable Polymers Used in Nanodrugs. International Journal of Nanomedicine, 8: 3071-3091, 2013
Tesis en proceso:
Principal tutor of students of the Doctorate Program in Biotechnology (INDICASAT- Acharya Nagarjuna University)
- Daniel Torres Mendoza. Chemical interactions of bacteria associated with marine invertebrates: Discovery of new compounds with Biomedical potential.
- Christopher Boya. Compounds with biomedical potential of actinomycetes associated with Atin ants..
- Christian Martin. Exploring the secondary biological and chemical diversity of bacteria associated with the skin of amphibians from Panama, Librada Atencio. Genomics-guided discovery of natural products of Pseudoalteromonas species associated with marine invertebrates.
- Candelario Rodríguez. Chemistry and biomedical potential of natural products from poison frogs.
Catherina Caballero, PhD
National Contact Point on Bioeconomy of the ALCUE net Network
Highest degree of studies: Doctorate, University of Antwerp, Belgium, 2002.
Category: Researcher
National Research System Level (SIN): Distinguished Researcher (2014), National Researcher Level I (2011).
Contact information:
E-mail: c.caballerogeorge@gmail.com,
ccaballero@indicasat.org.pa
Phone: +507 517 0737, +507 517 0700